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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDX6 All Species: 46.97
Human Site: Y217 Identified Species: 68.89
UniProt: P30041 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30041 NP_004896.1 224 25035 Y217 E L P S G K K Y L R Y T P Q P
Chimpanzee Pan troglodytes XP_001148286 209 23201 L198 A G V Q W R D L G P L Q P L P
Rhesus Macaque Macaca mulatta XP_001101473 224 25004 Y217 E L P S G K K Y L R Y T P Q P
Dog Lupus familis XP_537190 245 27431 Y238 E L P S G K K Y L R Y T P Q P
Cat Felis silvestris
Mouse Mus musculus O08709 224 24852 Y217 E L P S G K K Y L R Y T P Q P
Rat Rattus norvegicus O35244 224 24800 Y217 E L P S G K K Y L R Y T P Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515331 223 24797 Y216 E L P S A K R Y L R Y T P Q P
Chicken Gallus gallus Q5ZJF4 224 24958 Y216 D L P S G K K Y L R Y T P Q P
Frog Xenopus laevis NP_001082669 224 25051 Y216 E L P S G K K Y L R Y T A Q P
Zebra Danio Brachydanio rerio NP_957099 222 24990
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523463 222 24827 Y215 E L P S G K S Y L R I T P Q P
Honey Bee Apis mellifera XP_395319 220 24904 Y212 S L P S G K S Y V R I V S Q P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784500 189 21008 Y182 A V P S G K G Y I R L T P Q P
Poplar Tree Populus trichocarpa
Maize Zea mays A2SZW8 229 24887
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04005 216 24063 Y209 D L P S K K G Y L R H T E V S
Baker's Yeast Sacchar. cerevisiae P34227 261 29477 Y254 Q F N E I K P Y L R F T K S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.3 98.6 84.9 N.A. 89.7 91.5 N.A. 85.2 86.1 80.3 73.6 N.A. 60.2 59.3 N.A. 58
Protein Similarity: 100 87.5 99.5 89.3 N.A. 93.7 95 N.A. 91.5 93.7 87.5 86.1 N.A. 70 72.7 N.A. 63.8
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 86.6 93.3 93.3 0 N.A. 86.6 60 N.A. 66.6
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 93.3 100 93.3 0 N.A. 86.6 66.6 N.A. 80
Percent
Protein Identity: N.A. 51.5 N.A. 50.4 42.5 N.A.
Protein Similarity: N.A. 67.6 N.A. 66.5 56.3 N.A.
P-Site Identity: N.A. 0 N.A. 53.3 33.3 N.A.
P-Site Similarity: N.A. 0 N.A. 66.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 50 0 0 7 0 0 0 0 0 0 0 0 7 0 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 7 0 0 63 0 13 0 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 7 0 13 0 0 0 0 % I
% Lys: 0 0 0 0 7 82 44 0 0 0 0 0 7 0 7 % K
% Leu: 0 69 0 0 0 0 0 7 69 0 13 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 75 0 0 0 7 0 0 7 0 0 63 0 75 % P
% Gln: 7 0 0 7 0 0 0 0 0 0 0 7 0 69 0 % Q
% Arg: 0 0 0 0 0 7 7 0 0 82 0 0 0 0 0 % R
% Ser: 7 0 0 75 0 0 13 0 0 0 0 0 7 7 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 % T
% Val: 0 7 7 0 0 0 0 0 7 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 82 0 0 50 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _